Home > Shop by Skin Concern > Lightening & Brightening > Hydroquinone Based


How does hydroquinone work?

Hydroquinone works by decreasing the production and increasing the breakdown of melanosomes (melanin pigment granules) in the skin's pigment cells (melanocytes). It does this by inhibiting the activity of tyrosinase, the enzyme needed to make melanin.

How effective is hydroquinone?

In most cases, lightening of skin should be seen after 4 weeks of treatment. Sometimes it may take longer to see any change but if no bleaching effect is seen after 3 months of treatment, you should stop using hydroquinone.

To increase the effectiveness of hydroquinone you should stay out of the sun, or wear protective clothing and use a SPF30+ sunscreen when outdoors. Do not use sunlamps or tanning salons.

It is important to use hydroquinone regularly as directed until you achieve the desired bleaching, after which use only as needed to maintain results.

How to use hydroquinone

  • Test for skin sensitivity before using by applying the cream to a small patch of hyperpigmented skin. If no redness or itching occurs within 24 hours, begin treatment.
  • Clean and dry the skin before applying a thin film of cream twice daily to the area(s) in need of bleaching. Rub into the skin well.
  • Apply just enough to cover the affected areas and avoid applying to normal skin, as this will lighten as well. Hence wash your hands after applying unless these are areas of treatment.
  • Do not apply near the eyes, mouth, and other mucous membranes.
  • Avoid using other medicated topical products (particularly peroxide products) on the same area at the same time unless directed to do so by your doctor.
  • When using non-medicated cosmetics, sunscreens, and moisturising lotions, apply hydroquinone first, then wait several minutes before applying them over the top.
Sort By:
Page of 1
PCA Pigment Gel with HQ Sesha Clinical Advanced Lightening Serum
The penetrating triple-action of hydroquinone, kojic, and azelaic acids, plus AHAs helps to exfoliate, bleach, and inhibit hyperpigmentation and age spots. Sesha Clinical Advanced Lightening Serum is an advanced lightening formulation that includes hydroquinone and powerful lightening agents that increase cell-turnover rate and decrease deep melanin sediment. This complex serum reduces and inhibits tyrosinase activity to restore the skins natural tone.