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Some pigment reducers for lightening skin without the use of hydroquinone are vitamins like vitamin C, vitamin A, and vitamin B3 (niacin). Other herbs like emblica and licorice, and fruit acids like glycolic acid, also work.

Results with glycolic acid and retinoids show promise which is attributed to their ability to increase exfoliation. Retinoids also can help with melanosome transfer
A promising compound being used in OTC skin-lightening products is niacinamide. We know that as vitamin B3, some studies show that it does inhibit melanosome transfer, improving pigment transfer from melanocytes to keratinocytes.
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Neova Serious Clarity formerly Intense Brightening Complex PCA pHaze 13 Pigment Gel HQ Free CELLective Clinical Luminous Peptide Serum
Intense Brightening Complex:
* Targets the cause of skin discolorations
* Rapidly diminishes the appearance of discolorations
* Enables skin to achieve an even tone
* Powerful, yet safe, and effective treatment on all skin types
* Causes NO irritation or side effects
Formulated with kojic and azelaic acids, plus AHAs to effectively target various types of hyperpigmentation. It is ideal for hydroquinone sensitive or allergic complexions. CELLective Luminous Peptide Serum naturally brightens skin and reduces the wrinkle depth providing a lifting effect.

Palmitoyl Pentapeptide-4, a main ingredient in this serum, reduces wrinkle depth by 44% and increases lifting effect by 17%. Combine this with Daisy Flower Extract which reduces melanin formation and antioxidative activity, providing significant lightening effects.
Osmosis Pur Medical Skin Lightening Booster Blend NIA 24 Treatment Catalyst NIA 24 Skin Strengthening Complex Repair
Treatment Catalyst
Our Price: $71.00
Osmosis Pur Medical offers boosting agents in the form of powders that can be added to any treatment lotion, serum or cream to boost its effects on the skin.

Osmosis Pur Medical Lightening Booster Powder Blend utilizes a combination of amino acids that focus on treating and lightening pigmentation. Increase the efficacy of this powder by combining it with Vitamin C Powder Blend.
NIA24 Treatment Catalyst is a skin fortifying oil that contains patented Pro-Niacin, proven to visibly improve skin tone, texture & hyperpigmentation.

This nourishing formula delivers an immediate dose of moisture and radiance while reducing the overall appearance of fine lines and wrinkles.
Neither heavy nor too light, this fortified cream visibly reduces the appearance of fine lines and wrinkles by enhancing the skin's barrier function, accelerating repair and delivering continual moisturization.
CELLective Clinical DayGUARD Sesha Clinical Advanced Lightening Serum without HQ NIA 24 Intensive Recovery Complex
DayGUARD Active C&E + Peptides is a stable, effective and convenient antioxidant therapy for skin renewal and repair.

Traditional liquid serums can quickly degrade to the degree where the active ingredients no longer are effective. CELLective Clinical DayGUARD is a silky cream delivered in convenient single-use capsules that ensure you get fresh Vitamin C every time.

Stable 10% Vitamin C, 5% Vitamin E + Biopeptides softens, smoothes and gives your skin a healthy glow.
Clinical Advanced Lightening Serum without HQ, achieves pigmentation reduction using a state of art formulation with our patented delivery technology together with many advanced and natural ingredients synergistically to inhibit and reduce tyrosinase activity while combining the newest approach to gently stimulate the skin turnover rate by natural enzymes without any harsh reactions. NIA 24 Intensive Recovery Complex contains 5% Pro-Niacin along with the moisturizing benefits of sodium hyaluronate and ceramide 3. This product is an excellent choice for individuals with normal to extremely dry skin or individuals desiring additional moisturization. Contains a liposomal Complex of Vitamins A, C and E and Ceramide 3.