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Some pigment reducers for lightening skin without the use of hydroquinone are vitamins like vitamin C, vitamin A, and vitamin B3 (niacin). Other herbs like emblica and licorice, and fruit acids like glycolic acid, also work.

Results with glycolic acid and retinoids show promise which is attributed to their ability to increase exfoliation. Retinoids also can help with melanosome transfer
A promising compound being used in OTC skin-lightening products is niacinamide. We know that as vitamin B3, some studies show that it does inhibit melanosome transfer, improving pigment transfer from melanocytes to keratinocytes.
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PCA Perfecting Protection SPF 30 PCA pHaze 13 Pigment Bar Rhonda Allison NATURALE MEGA BRIGHTENING SERUM
Pigment Bar - pHaze 13
Our Price: $38.00
NEW! PCA Perfecting Protection SPF 30 is a revolutionary broad-spectrum UVA/UVB product that combines the superior protective benefits of Z-Cote and other potent sunscreen agents with five melanogenesis inhibitors.
This unique blend of ingredients works to reduce existing skin discoloration while preventing future hyperpigmentation. In addition, potent antioxidants caffeine and silybum marianum extract, commonly referred to as milk thistle, work to fight damaging environmental free radicals, inflammation and the formation of sunburn cells.
The cleansing companion in our pigment control program designed to enhance and maintain even skin tone. Also recommended for large areas of treatment. Use once daily, alternate with the appropriate pHaze 1 Facial Wash. Rhonda Allison Naturale Mega Brightening Serum offers the benefits of natural plant extracts and herbs for serious skin brightening and maintenance are increased by the synergy of this powerful mega complex.
Neova Serious Clarity formerly Intense Brightening Complex PCA pHaze 13 Pigment Gel HQ Free CELLective Clinical Luminous Peptide Serum
Intense Brightening Complex:
* Targets the cause of skin discolorations
* Rapidly diminishes the appearance of discolorations
* Enables skin to achieve an even tone
* Powerful, yet safe, and effective treatment on all skin types
* Causes NO irritation or side effects
Formulated with kojic and azelaic acids, plus AHAs to effectively target various types of hyperpigmentation. It is ideal for hydroquinone sensitive or allergic complexions. CELLective Luminous Peptide Serum naturally brightens skin and reduces the wrinkle depth providing a lifting effect.

Palmitoyl Pentapeptide-4, a main ingredient in this serum, reduces wrinkle depth by 44% and increases lifting effect by 17%. Combine this with Daisy Flower Extract which reduces melanin formation and antioxidative activity, providing significant lightening effects.
Osmosis Pur Medical Skin Lightening Booster Blend NIA 24 Sun Damage Repair for Chest and Hands Osmosis ENLIGHTEN Pigmentation Skin Serum
Osmosis Pur Medical offers boosting agents in the form of powders that can be added to any treatment lotion, serum or cream to boost its effects on the skin.

Osmosis Pur Medical Lightening Booster Powder Blend utilizes a combination of amino acids that focus on treating and lightening pigmentation. Increase the efficacy of this powder by combining it with Vitamin C Powder Blend.
This nutrient-rich cream delivers intense moisture while it improves the appearance of photo-damage on the decolletage (chest), shoulders and hands.
Age spots and discolorations visibly diminish with this proven brightening complex. Enhances skin barrier function to accelerate repair and increase resistance to damage and moisture loss. Daily use results in significant improvement in overall tone, texture and resilence. Contains 2.5% Pro-Niacin and brightening agents.

Hydroquinone-Free

Osmosis ENLIGHTEN dramatically lightens the skin due to its many liposome-coated tyrosinase inhibitors which reach the basal layer more effectively. It calms inflammation, may assist the skin in remodeling scarring from photodamage, hydrates, and protects against UV rays.

NIA 24 Treatment Catalyst NIA 24 Rapid Depigmentation Serum Pevonia LumaFirm Repair Cream Lift and Glow
Treatment Catalyst
Our Price: $71.00
NIA24 Treatment Catalyst is a skin fortifying oil that contains patented Pro-Niacin, proven to visibly improve skin tone, texture & hyperpigmentation.

This nourishing formula delivers an immediate dose of moisture and radiance while reducing the overall appearance of fine lines and wrinkles.
Get rid of age spots fast with NIA24 Rapid Depigmentation Serum.

See a significant improvement in your complexion with this NIA24 treatment for hyperpigmentation. NIA 24 Rapid Depigmentation Serum contains a mix of concentrated, clinically proven ingredients that improve skins tone and texture while it fades age spots. This lightweight serum penetrates into the deep layers of your skin, effectively targeting the signs of hyperpigmentation at the source. With continued use, you will quickly notice a brighter, clearer complexion with fewer age spots.
Pevonia LumaFirm Repair Cream Lift and Glow is known to Firm, lighten, brighten, smooth, repair and protect with this lightweight, anti-aging moisturizer that truly delivers immediate and cumulative results.

Experience immediate and visible firmness and brightness.
NIA 24 Skin Strengthening Complex Repair CELLective Clinical DayGUARD Sesha Clinical Advanced Lightening Serum without HQ
Neither heavy nor too light, this fortified cream visibly reduces the appearance of fine lines and wrinkles by enhancing the skin's barrier function, accelerating repair and delivering continual moisturization. DayGUARD Active C&E + Peptides is a stable, effective and convenient antioxidant therapy for skin renewal and repair.

Traditional liquid serums can quickly degrade to the degree where the active ingredients no longer are effective. CELLective Clinical DayGUARD is a silky cream delivered in convenient single-use capsules that ensure you get fresh Vitamin C every time.

Stable 10% Vitamin C, 5% Vitamin E + Biopeptides softens, smoothes and gives your skin a healthy glow.
Clinical Advanced Lightening Serum without HQ, achieves pigmentation reduction using a state of art formulation with our patented delivery technology together with many advanced and natural ingredients synergistically to inhibit and reduce tyrosinase activity while combining the newest approach to gently stimulate the skin turnover rate by natural enzymes without any harsh reactions.
Sircuit Brilliance Pigment Correction Serum NIA 24 Intensive Recovery Complex
Sircuit Skin Brilliance Fading Serum - formulated with 4% L- Arbutin and 2% Lactic Acid. This unique serum is also fortified with a special new Neem Leaf Extract that has specific brightening benefits and a Lemon Peel Extract with the ability to help reduce hyper-pigmentation and even out skin tone. NIA 24 Intensive Recovery Complex contains 5% Pro-Niacin along with the moisturizing benefits of sodium hyaluronate and ceramide 3. This product is an excellent choice for individuals with normal to extremely dry skin or individuals desiring additional moisturization. Contains a liposomal Complex of Vitamins A, C and E and Ceramide 3.